(Image: Supplied)
Researchers have reached a milestone in a study examining why some people become critically ill from infections while others suffer only mild symptoms.
The critical care research team at James Cook University Hospital has recruited more than 850 patients for the GENOMICC study into the genetics of severe infections.
The study aims to identify genetic factors that leave some people needing intensive care while others suffer only mild symptoms.
Jeremy Henning, critical care consultant and principal investigator at James Cook, said: "Infections affect millions of people around the world every year – including so many patients we treat in this unit.
"Most cases are mild, but some people become very unwell and are admitted to intensive care.
"Our DNA can determine how much critical illness affects us.
"The study team want to find the genes that cause some people to be more sick.
"If we do, we may be able to develop better treatments for patients in the future."
Researchers hope the genetic findings will improve treatment for conditions such as sepsis, a life-threatening reaction to infection.
Jess Jones, a critical care research nurse at James Cook, said: "The study has been running now for several years and, over that time, we have been the top recruiting site on several occasions – including being top in June and July this year.
"All it involves is one simple blood test and can potentially make such a difference.
"Patients are often happy to help, getting comfort in knowing they are helping shape and improve healthcare.
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"A huge thank you to all of our patients who have taken part and to the staff on critical care for supporting us in the delivery of this study."
The GENOMICC study is also running at nearby University Hospital of North Tees through a joint research alliance within the University Hospitals Tees health group.
More information about the study is available at genomicc.org/participants.